Studies on the Internalization Mechanism of Cationic Cell-penetrating Peptides
نویسندگان
چکیده
منابع مشابه
Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization.
Cationic cell-penetrating peptides (CPPs) have been used widely as delivery vectors for the import of molecules that otherwise do not cross the plasma membrane of eukaryotic cells. In this work, we demonstrate that the three cationic CPPs, Antennapedia homeodomain-derived peptide (Antp), nona-arginine and Tat-derived peptide, inhibit tumour necrosis factor (TNF)-mediated signal transduction. Th...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2003
ISSN: 0021-9258
DOI: 10.1074/jbc.m303938200